CHM3922 · Advanced organic chemistry

Overview

A description of the advanced tools and methodologies that are used in the determination of reaction mechanisms will be provided. This is supported by a discussion of the theoretical basis of the design of synthetic pathways for target e.g. bioactive molecules. The knowledge gained will be used to elucidate the reaction mechanisms of common organic reactions and metal-mediated reactions towards identifying scope in organic chemistry. The development of chemical methods that allow realisation of the concept of a sustainable future will also be discussed. Advanced NMR spectroscopy will also be introduced as a useful tool to elucidating structure.

Areas of study: Chemistry Medicinal chemistry

Offerings

Assessment

The Handbook lists an examination for this unit.

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Requisites

The Handbook lists no prerequisite, corequisite or prohibition for this unit.

Learning outcomes

1. Identify and operate standard chemical laboratory apparatus to undertake and analyse routine organic transformations;
2. Identify and design strategies that exploit conjugate addition reactions;
3. Understand the rationale behind the design of strategies to assemble complex aromatic materials;
4. Identify and describe common pericyclic reactions;
5. Identify and understand routine transition metal catalysed and organocatalytic chemical reactions.

Workload

• Three 1-hour workshops; • One hour directed independent study per week and • the equivalent of 3 hours of laboratory activity per week

Student experience, not official rules. Nothing here changes what the Handbook says.