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MCE5201 · Advanced skills: Embryo manipulations

Official Handbook

2026 Handbook12 credit pointsLevel 5Department of Obstetrics and Gynaecology

Last checked: 23 Aug 2026 UTC

Overview

This unit will build on the assisted reproduction technology (ART) practical skills gained in MCE5112. Hands-on practical tuition will enable you to gain an appreciation for more advanced embryology skills. Using a murine model, you will gain competency in embryo vitrification, embryo warming and micromanipulation (intracytoplasmic sperm injection [ICSI] and biopsy). You will demonstrate a comprehensive understanding of key ART processes though both practical and written assessments. Associated laboratory skills such as laboratory etiquette, working as a group, liquid nitrogen training and writing laboratory reports will be included in the teaching of this unit. Note; dissecting mice and attending the animal house for gamete and embryo collection is optional for you.

Offerings

CampusTeaching periodMode
Monash Medical CentreSecond semester (extended)Teaching activities are on-campus (ON-CAMPUS)

Assessment

The Handbook lists an examination for this unit.

#AssessmentTypeWeightHurdle
1Practical skills assessment: Vitrification and warming (3-4 hours)Demonstration35%Competency
2Practical skills assessment: Intracytoplasmic sperm injection (ICSI) (3-4 hours)Demonstration35%Competency
3Practical skills assessment: Objective structured practical examination (OSPE) (2 x 1hrs)Demonstration20%
4Reports (x10)Artefact10%

Assessment in this unit includes hurdle assessment tasks. Failure of any hurdle assessment task may result in failure of the unit

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Requisites

The Handbook lists no prerequisite, corequisite or prohibition for this unit.

Learning outcomes

  1. Synthesise knowledge and skills to successfully vitrify and warm embryos without compromising developmental potential
  2. Model advanced micromanipulation techniques, including ICSI and embryo biopsy, to achieve optimal laboratory outcomes in assisted reproduction technology (ART).
  3. Interpret and apply laboratory protocols and standard operating procedures (SOPs) in a laboratory setting.
  4. Integrate and advocate Occupational Health, Safety and Environment (OHSE) principles into daily laboratory practices, ensuring safety in ART
  5. Optimise the use of laboratory consumables, equipment, and reagents, applying evidence-based reasoning for enhanced efficiency and reliability in assisted reproductive technology (ART).
  6. Formulate solutions to complex problems in unexpected laboratory scenarios where real-time problem-solving is required.
  7. Synthesize experimental data and laboratory observations to produce actionable insights, addressing industry needs

Workload

This is a practical based unit, with a high number of contact hours for hands-on training. For on-campus students, this unit is conducted throughout all of Semester 2 (18 weeks), with up to 16 hours per week of directed and self-directed learning. It is expected that you attended all practical sessions and tutorials associated with this unit. Off-campus students need to be working in an ART clinical to complete or gain credit for MCE5201 or you will need to attend face-to-face. During some practical blocks, daily attendance will be required.

ActivityDuration
Applied sessions
Tutorials6 hours

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