BMS1132 · The molecular basis of life

Overview

In this unit, you will explore the core principles of molecular biology and biochemistry that underpin the flow of genetic information and cellular function. Students will examine how genetic information is stored, replicated, and expressed through DNA replication, transcription, and translation, and compare how these processes are regulated in prokaryotic and eukaryotic cells. You will investigate protein structure and function, including enzymatic activity, energy production, and the mechanisms that direct protein trafficking and sorting within eukaryotic cells. You will also investigate DNA mutation, recombination, and the molecular systems responsible for DNA repair and maintenance, and the impact these have on health and disease. You will develop practical skills using contemporary molecular techniques, alongside the ability to interpret and critically analyse experimental data. A key focus will be on the application of scientific reasoning to real-world biomedical problems and communicating scientific information effectively through written, oral, and visual formats.

Offerings

Assessment

The Handbook lists an examination for this unit.

Assessment in this unit includes hurdle assessment tasks. Failure of any hurdle assessment task may result in failure of the unit.

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Requisites

Learning outcomes

1. Explain the molecular mechanisms that allow the storage, inheritance and expression of genetic information, specifically the processes of genome replication, gene transcription and mRNA translation.
2. Compare and contrast the regulatory mechanisms that control cell function at the levels of RNA synthesis, mRNA processing and protein activity in prokaryotic and eukaryotic cells.
3. Differentiate the various mechanisms of protein trafficking within eukaryotic cells, including how proteins are targeted and transported to, and sorted between organelles.
4. Explain the relationship between the structure and function of proteins as the main machinery of the cell, including the principles of enzymatic activity and energy production.
5. Assess the causes and consequences of DNA mutation and recombination, and describe the molecular mechanisms involved in DNA maintenance and repair.
6. Use molecular tools and technologies to perform, interpret and critically analyse experiments in biomedical sciences.
7. Apply scientific reasoning skills and knowledge in molecular biology and biochemistry to investigate real-world scenarios in biomedical sciences.
8. Present, describe and discuss scientific information and experimental data using appropriate written, verbal and visual formats.
9. Demonstrate personal and professional responsibility, employing reflective practice for ongoing development.

Workload

Approximately 11 hours of teacher directed study per week, including 4 hours of lectures, 2 hours of pre/post-class modules, 2 hours of workshops and 3 hours of laboratories. Approximately 12-13 hours per week of self-directed study. Total per week = Up to 24 hours

Student experience, not official rules. Nothing here changes what the Handbook says.