BCH2022 · Metabolic basis of human diseases

Overview

This is the second of two units in the Biochemistry second year curriculum which introduces you to the fundamental concepts and knowledge required to understand cellular function at a molecular level. The unit will assist you to build the skills necessary to interpret biochemical information and perform biochemical experiments. The curriculum builds on foundational knowledge of cell biology and organic and physical chemistry, establishes the skills and understanding needed for the more specialised third year biochemistry units. It also provides you with a broad appreciation of cellular processes relevant to all areas of life. In this unit (Metabolic basis of human diseases), you will learn about the mechanisms by which biochemical processes are activated, suppressed and coordinated in pathways/networks to maintain cell and organism viability and to respond appropriately to environmental stimuli. These mechanisms are examined within the context of cellular respiration and energy metabolism and the dysregulation of biochemical pathways is related to human disease. Skill development focuses on analysis and measurement of metabolic and signalling processes and on testing hypotheses related to biochemical pathways and networks.

Areas of study: Biochemistry

Offerings

Assessment

The Handbook lists an examination for this unit.

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Requisites

The Handbook lists no prerequisite, corequisite or prohibition for this unit.

Learning outcomes

1. Describe the role of cellular respiration in the maintenance of life;
2. Integrate the various energy producing biochemical pathways demonstrating interrelationships and regulation;
3. Apply the principles of regulation to explain how biochemical pathways are coordinated;
4. Analyse how dysregulation of biochemical pathways is related to human diseases;
5. Communicate scientific information effectively through written or verbal means;
6. Apply scientific methodologies and laboratory techniques to collect, analyse, and draw conclusions from data.

Workload

• 3 hours of laboratory class activities • 2 hours of workshops and online activities and • 6 hours of independent study per week

Student experience, not official rules. Nothing here changes what the Handbook says.