GEN2052 · Genomics and population genetics

Overview

The structure, function, variation and evolution of DNA and of genomes are examined at both the individual and population levels in a range of organisms, including humans. Topics include: genome structure and approaches to genome analysis; basic principles and practical use of bioinformatics methods for genome projects; functional and comparative genomics; evolution of gene families and movement of genes from organelle to nuclear genomes; genome variation between individuals and species and its applications in genetics; processes that change the genetic constitution of populations and species during evolution.

Areas of study: Genetics

Offerings

Assessment

The Handbook does not list a final examination among the assessment items. That is not a guarantee there is none.

Assessment details may change. Please refer to the assessment information in Moodle closer to the start of the teaching period.

Requisites

Learning outcomes

1. Explain how genes are organised in chromosomes and genomes and the implications of this for gene expression and function, how genomes are mapped and sequenced, how genes and genomes are analysed at a molecular level, and the uses of genomics in modern genetic research;
2. Explain how DNA and genomes change and the implications of this for evolution and the uses of DNA variation in modern applications such as DNA profiling;
3. Explain how genes behave in populations, describe concepts such as mutation and genetic drift, and illustrate how genetic variation can result in fitness differences that may drive evolution through the process of natural selection;
4. Investigate the relevance and value of genetics and genomic to human society;
5. Demonstrate communication skills to to synthesise and convey complex concepts to peers and non-specialist audiences;
6. Demonstrate basic experimental, bioinformatics and statistical techniques to collect, interpret and analyse data, and solve genetic problems.

Workload

• 2.5 hours of online activities; • 1 hour of workshop; • 2 hours of laboratory and • 6.5 hours of independent study per week

Student experience, not official rules. Nothing here changes what the Handbook says.